Аннотация:
The study included 63 patients with alcohol withdrawal syndrome (AAS) moderate to severe. Sodium hypochlorite (GHN) was used in 31 patients (observed group). Infusion was performed through the solution GHN kateter installed in any endogenously main vein, at a concentration of 600 mg / l in a volume of 400 ml with an average rate of 80 drops per minute. For an objective assessment of endogenous intoxication (EI) was determined diene conjugates (DC), malondialdehyde (MDA), medium molecular peptides (SMP) and urea in the dynamics – the outcome of the 1 – and 3 rd day. The degree of EI examined by a combined indicator – KEI ratio: KEI = (DCT / DTC) (MDAp / mdaN) (SMPP / SMPn) (MOChEVINAp / MOChEVINAn), where n – pathology; n – the average value of the norm. We establish the presence of EI patients c AAS to increase DC, MDA, SMP and urea. Estimation based on KEI EI is more informative to compare these parameters individually. Using KEI facilitates the timely appointment of adequate detoxification
Ключевые слова:
alcohol withdrawal syndrome, sodium hypochlorite, endogenous intoxication, the ratio of endogenous intoxication