Аннотация:
Intake of 40° alcohol in amounts of 200 g or higher during a period of 1 – 3 days by healthy persons causes damage to innate immunity and cytokine profile, namely, a decrease in cytolytic activity of NK-cells, increase in oxygen dependent activity of phagocytic cells, and a decrease in their absorbing and digesting activity. Along with these effects of ethanol, the hemolytic activity of complement increases and the C4 complement component decreases, circulating immune complexes increase and cytokines IL2 and interferon- decrease in blood sera.
Ключевые слова:
alcohol intoxication, healthy individuals, inborn immuntitet, NK-cells, cytokines