Аннотация:
Monoaminergic brain systems are involved in the formation of positive and negative emotions. Norepinephrine, dopamine and serotonin are located in the basal ganglia and limbic system, which regulate animal behavior, emotional reactions and motor activity. The aim of this work was to study the features of the turnover of monoamines in the terminal structures of the mesocorticolimbic and nigrostriatal systems: the nucleus accumbens and striatum during stimulation of the positive and negative emotiogenic zones of the lateral hypothalamus. Electrical stimulation of the positive and negative emotiogenic zones of the hypothalamus increases the turnover of dopamine and serotonin in the nucleus accumbens and striatum. However, these changes are more pronounced upon stimulation of the positive emotiogenic zones of the hypothalamus as compared with negative emotiogenic zones. The structural specificity of the observed changes is also noted. The turnover of dopamine is more increased in the nucleus accumbens, and the turnover of serotonin in the striatum.
Ключевые слова:
dopamine, serotonin, norepinephrine, nucleus accumbens, striatum lateral hypothalamus, self-stimulation, aversive stimulation.