Аннотация:
Aim: to evaluate the effectiveness of methods of normoxic therapeutic compression and hyperbaric oxygenation in combination with standardized drug therapy based on the dynamics of indicators of biological markers of the acid-base state during the relief of alcohol withdrawal syndrome to optimize the treatment process.
Methods. A comparative assessment of the acid-base state in alcohol withdrawal syndrome was made in 3 groups of patients who underwent: treatment with drugs only (CG) and two comparison groups who underwent complex drug therapy in combination with methods of normoxic therapeutic compression and hyperbaric oxygenation. The basic and calculated indicators of the acid-base state in dynamics were evaluated against the background of the therapy.
Results. The use of oxygen therapy methods in combination with drugs allows, in a shorter time and effectively, to correct the main indicators of the acid-base state, mainly due to the actualization of the functioning of the carbonate buffer system. There is a specificity of the effect of each method of oxygen therapy in the complex treatment of alcohol withdrawal syndrome on various components of the main condition.
Conclusion. Laboratory diagnostics of the acid-base state can be used to objectify the effectiveness of the ongoing therapeutic measures using the methods of normoxic therapeutic compression and hyperbaric oxygenation in combination with drug therapy for alcohol withdrawal.
Ключевые слова:
alcohol withdrawal syndrome, acid-base state, hyperbaric oxygenation, normoxic therapeutic compression, treatment.