Аннотация:
The review article considers the historical aspects, the current state and prospects of studying the problem of the use of drugs of the group of neuroleptics in psychopharmacotherapy of chemical dependence. The need for research into the feasibility of using drugs of the group of neuroleptics for the treatment of drug patients, in particular, to stop pathological craving for psychoactive substances is substantiated. The authors argue that such research should be performed using pharmacoepidemiological approach, at the same time defining the benefit-risk ratio as well as studying relative effectiveness of therapeutic regimens, including and excluding antipsychotics, with orientation towards the result, consisting not in formal "reduction of craving", but in achieving the ultimate goal of the whole treatment and rehabilitation process, i.e. improvement of patient’s life quality and his return to treatment and rehabilitation.
Ключевые слова:
neuroleptics, antipsychotics, pharmacoepidemiology, evidence-based medicine, psychopharmacotherapy, rehabilitation.