Аннотация:
Introduction. In the structure of non-chemical addictive disorders, which are based on non-chemical addiction (gambling and computer games, Internet addiction, workaholism, etc.), various emotional disorders are distinguished. The premorbid period in various patients with addiction to psychoactive substances manifested in different ways such a phenomenon as "exploratory drug addiction", where there were different initial motives for using psychoactive substances, and the society of these individuals also exerted its influence when they were involved in systematic drug addiction, which had in its manifestation one or another affective coloring.
Aim. To conduct analysis of the contribution of daily-seasonal rhythm of affect to the structure of disease development among patients with opioid use disorder.
Methods. The study was carried out on the basis of the Moscow Scientific and Practical Center of Narcology (MSaPCoN). The research was conducted on 122 hospitalized patients (75 men and 47 women) aged 18 to 55 years (mean age 34,58 ± 0,15 years), with opioid use disorder, in whose mental status the leading or significant place was occupied by affective disorders, who were treated at the MSaPCoN in 2015-2016 and participated in the study "Affective disorders in patients with opioid use disorder". A special survey card was filled out for each respondent, which included gender, genetic heredity, as well as the results of the examination obtained with the help of clinical, clinical and psychopathological techniques.
Results. The daily and seasonal rhythms of affect were assessed. Based on this indicator, it was found that a shorter period of a searching stage narcotism (up to a month) prevailed (p=0,02616) (OR = 0,426; 95% CI 0,195– 0,934) in the group where there was no correlation with the seasonal and daily rhythm of affect. The presence of non-chemical predilections in premorbide was revealed among the study respondents who had seasonal and daily rhythms of affect (p=0,00719) (OR = 2,842; 95% CI 1,312– 6,157).
Conclusions. Daily and seasonal rhythm of affect was a factor slowing the pace of development and formation of opioid addiction. The presence of non-chemical use disorders in the premorbid development of opioid use disorder is a "marker" of the presence / formation of affective disorders of the endogenous spectrum.
Ключевые слова:
daily and seasonal rhythm of affect, predilections, opioid use disorders